NtRPC can't handle Binary right now at all, but even on a REST API where you can stream files/binary around it's not advisable to send 500mb through your API
NBest bet really is S3 and presigned URLs, or some equivalent like Azure Storage with SaS URLs
NIf you really want to do it, you can host tRPC inside Express/Fastify/(etc) and handle the file uploads in the web servers